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Saturday, 9 June 2012

Estrogen Hormone Replacement: The Replacement To Stay Young Forever

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By Jake Alexandre


Estrogen are a group of steroid amalgam, named for their importance in the estrous cycle, and functioning as the primary female sex hormone, their name comes from estrus/oistros (period of fertility for female mammals) + gen/gonos = to generate. Estriol is the primary estrogen of pregnancy. In the body these are all produced from androgens through actions of enzymes. Estrogens are used as part of some oral contraceptives, in estrogen hormone replacement for postmenopausal women, and in hormone replacement therapy for Tran's women.

Menopause is the result of changing hormones, specifically estrogen and progesterone. In women, these characteristics include breasts, a widened pelvis, and increased amounts of body fat in the buttock, thigh and hip region. Estrogen also contributes to the fact that women have less facial hair and smoother skin then men. It regulates the menstrual cycle and prepares the uterus for pregnancy by enriching and thickening the endometrial. Two hormones, the luteinizing hormone (LH) and the follicle stimulating hormone (FSH), help to control how the body produces estrogen in women who ovulate. When the delicate coordination of FSH and estrogen is disturbed doctors suggest estrogen hormone replacements

In females, synthesis of estrogens starts in theca internal cells in the ovary, by the synthesis of androstenedione from cholesterol. Androstenedione is a substance of moderate androgenic activity. This compound crosses the basal membrane into the surrounding granulosa cells, where it is converted to estrone or estradiol, either immediately or through testosterone. The conversion of testosterone to estradiol, and of androstenedione to estrone, is catalyzed by the enzyme aromatase. Fluctuations in estrogen can have dramatic effects on how we feel, think, and function.

Compared to other hormones, estrogen is very tightly regulated by the body, and it's more powerful in smaller amounts than other steroid hormones. and hence it s needed to be replaced. Estrogen replacement refers to taking regular doses of estrogen, usually the lowest effective doses, to replace the natural estrogen that decreases at menopause. Estrogen hormone replacement is often recommended to relieve these symptoms associated with menopause severe hot flashes sleeplessness vaginal dryness, resulting in discomfort or pain during sexual intercourse.

When the estrogen levels decrease and the menopause starts, then the main risks become osteoporosis and arteriosclerosis. This is the reason why doctors tend to prescribe estrogen hormone replacement as a therapy Estrogen hormone replacement is considered as drug that would improve the quality of life during menopause. However, as the active hormones have other important functions in the body; it is possible to have unwanted effects. Not all women experience symptoms of menopause; however, for those that do, other than estrogen hormone replacement and natural menopause treatment can also helps in reducing a wide range of symptoms that may bring misery to a woman's senior years. Estrogen replacement intervenes in various cancers. High level of estrogen can increase the risk for breast cancer. Conventional hormone therapy is not the only option available.




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